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89 mg/mL(197
with the IC50 of 6
CAS Number: 172889-27-9
5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-1
InChi: InChI=1S/C29H26ClF3N2O6/c1-39-22-11-20(12-23(13-22)40-15-18-10-24(18)28(37)38)34-26(17-2-5-19(30)6-3-17)27(36)35-9-8-16-4-7-21(14-25(16)35)41-29(31
Zaragozic Acid A Catalog No.:M22482-C 89 mg/mL(197Ki: 78 pM for rat liver squalene synthase The zaragozic acids (ZAs), which is a family of fungal metabolites containing a novel 4,6,7 trihydroxy 2,8 dioxobicyclo[3. 2. 1]octane 3,4,5 tricarboxylic acid core, have been independently discovered by two separate groups via screening natural product sources to discover inhibitors of squalene synthase. In vitro: Zaragozic acid A, as well as it two analogs Zaragozic acid B and C were discovered from an
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