SNDX-5613 - CAS# 2169919-21-3 midone 28)22-31-20(32-35-22)17-7-4-8-18(13-17)21(33)29-15-24(9-11-34-12-10-24)23-30-19(14-36-23)16-5-2-1-3-6-16/h1-8

28)22-31-20(32-35-22)17-7-4-8-18(13-17)21(33)29-15-24(9-11-34-12-10-24)23-30-19(14-36-23)16-5-2-1-3-6-16/h1-8

X-Gluc Dicyclohexylamine is used as a reagent to detect β-glucuronidase

PFI-3 was used at 1-10 µM final concentration in various in vitro assays

Smiles: CC(C)(SC1=CC=C(CCN(CCCCC2CCCCC2)C(=O)NC2CCCCC2)C=C1)C(O)=O

4-c]pyridin-3-one

SNDX-5613 - CAS# 2169919-21-3 midone 28)22-31-20(32-35-22)17-7-4-8-18(13-17)21(33)29-15-24(9-11-34-12-10-24)23-30-19(14-36-23)16-5-2-1-3-6-16/h1-8SNDX 5613 is a potent and selective inhibitor of menin MLL binding with a Ki of 0. 15 nM. SNDX 5613 shows anti proliferative activity against multiple cell lines harboring MLLr translocations (MV4; 11, RS4; 11, MOLM 13, KOPN 8) with IC50 values ranging from 10 20 nM. Product information CAS Number: 2169919 21 3 Molecular Weight: 630. 82 Formula: C32H47FN6O4S Chemical Name: N ethyl 2 [4 [7 [[4 (ethylsulfonylamino)cyclohexyl]methyl] 2, 7 diazaspiro[3.