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60 mg/kg) reduces tumor growth of HCT116 cells in a xenograft model
ML-180 yridin-2-yl)ethane-1 2-diamine hydrochloride 60 mg/kg) reduces tumor growthML 180 (SR1848) is a potent orphan nuclear receptor liver receptor homolog 1 (LRH 1; NR5A2) inverse agonist with an IC50 of 3. 7 M. ML 180 is inactive for steroidogenic factor 1 (SF 1; NR5A1; IC50>10 M). ML 180 has the potential for LRH 1 dependent cancers . Product information CAS Number: 863588 32 3 Molecular Weight: 388. 89 Formula: C20H25ClN4O2 Chemical Name: 6 [4 (3 chlorophenyl)piperazin 1 yl] 3 cyclohexyl 1H pyrimidine 2,4 dione Smiles:
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