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The IC50 for AG14361 is 29 nM in permeabilized SW620 cells and 14 nM in intact SW620 cells
COC1=CC=C(CCCOC(CN2C=NC=C2)C2C=CC(=CC=2)OC)C=C1
Formula: C24H27FN2O4
leading to apoptosis without the need for a Smac mimetic in a variety of cancer cell lines
FANCD1/BRCA2 plays predominant role in the repair of DNA damage induced by ACNU or TMZ
2'-Deoxyadenosine chionide A The IC50 for AG14361 is2' Deoxyadenosine is a nucleoside adenosine derivative, pairing with deoxythymidine (T) in double stranded DNA. Product information CAS Number: 958 09 8 Molecular Weight: 251. 24 Formula: C10H13N5O3 Chemical Name: (2R,3S,5R) 5 (6 amino 9H purin 9 yl) 2 (hydroxymethyl)oxolan 3 ol Smiles: NC1=NC=NC2=C1N=CN2[C@H]1C[C@H](O)[C@@H](CO)O1 InChiKey: OLXZPDWKRNYJJZ RRKCRQDMSA N InChi: InChI=1S C10H13N5O3 c11 9 8 10(13 3 12 9)15(4 14 8)7 1 5(17)6(2 16)18 7 h3
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