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Formula: C17H15NO3
STO-609 inhibits the activities of recombinant CaM-KK alpha and CaM-KK beta isoforms
is a potent and selective IDH2 inhibitor with potential anticancer activity (IDH2 = Isocitrate dehydrogenase 2)
Abstract 3679
InChi: InChI=1S/C18H10F3NO3S2/c19-18(20
ROC-325 - CAS# 1859141-26-6 size:2mg solid Formula: C17H15NO3ROC 325, CAS No. 1859141 26 6, is an autophagy inhibitor. ROC 325 exhibited superior in vitro anticancer effects compared with the existing autophagy inhibitor hydroxychloroquine (HCQ) in 12 different cancer cell lines with diverse genetic backgrounds. ROC 325 antagonized RCC growth and survival in an ATG5 7 dependent manner, induced apoptosis, and exhibited favorable selectivity. Product information CAS Number: 1859141 26 6 Molecular Weight: 503. 06
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