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KCC2 blocker 1 543AT-1251 100 μM) significantly improves islet

SKU: 33368071665

4.2
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Description

100 μM) significantly improves islet function following isolation and improves islet graft function following transplantation in mice model

InChiKey: GCWIQUVXWZWCLE-INIZCTEOSA-N

2-Pyridineacetamide

is over-produced in the human neurometabolic disease D-α-hydroxyglutaric aciduria

InChi: InChI=1S/C18H20N6OS/c1-12-16(26-17(19)21-12)15-6-7-20-18(23-15)22-13-2-4-14(5-3-13)24-8-10-25-11-9-24/h2-7H

KCC2 blocker 1 543AT-1251 100 μM) significantly improves isletKCC2 blocker 1 is an orally active and selective K+ Cl cotransporter KCC2 blocker with an IC50 of 1 M. KCC2 blocker 1 is a benzyl prolinate and has antiepileptic effect. Product information CAS Number: 1228439 36 8 Molecular Weight: 415. 50 Formula: C22H25NO5S Chemical Name: benzyl 1 acetyl 2 [(4 methanesulfonylphenyl)methyl]pyrrolidine 2 carboxylate Smiles: CC(=O)N1CCCC1(CC1C=CC(=CC=1)S(C)(=O)=O)C(=O)OCC1C=CC=CC=1 InChiKey: XFXZWVGQXNFWDE UHFFFAOYSA

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