GSK-1070916 Catalog No.:M10968-10 C4H6O5/c1-5-27(6-2)10-9-24-22(29)20-13(3)19(25-14(20)4)12-17-16-11-15(23)7-8-18(16)26-21(17)28

Name: GSK-1070916 Catalog No.:M10968-10 C4H6O5/c1-5-27(6-2)10-9-24-22(29)20-13(3)19(25-14(20)4)12-17-16-11-15(23)7-8-18(16)26-21(17)28
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Description

C4H6O5/c1-5-27(6-2)10-9-24-22(29)20-13(3)19(25-14(20)4)12-17-16-11-15(23)7-8-18(16)26-21(17)28

KW-2449 has little effect on PDGFRÎ²

InChiKey: CSEVDQHYSARWTE-UHFFFAOYSA-N

PQR-309 also inhibits PI3Kα-H1047R)

Kunapuli SP

GSK-1070916 Catalog No.:M10968-10 C4H6O5/c1-5-27(6-2)10-9-24-22(29)20-13(3)19(25-14(20)4)12-17-16-11-15(23)7-8-18(16)26-21(17)28GSK1070916, also known as NMI 900 or GSK 1070916A, is an ATP competitive inhibitor of the serine threonine kinases Aurora B and C with potential antineoplastic activity. Aurora B C kinase inhibitor GSK1070916A binds to and inhibits the activity of Aurora kinases B and C, which may result in inhibition of cellular division and a decrease in the proliferation of tumor cells that overexpress the Aurora kinases B and C. Product information CAS Number:

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