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CAS Number: 1127442-82-3
Binding Modes of Small-Molecule Inhibitors to the EED Pocket of PRC2
It induces degradation of EGFR in OVCAR8 cells
it is the muscle present in places such as the gut and uterus
with IC50 values of between 2
Metolazone uolin-1 CAS Number: 1127442-82-3Metolazone is a thiazide like diuretic. It is primarily used to treat congestive heart failure and high blood pressure. Metolazone indirectly decreases the amount of water reabsorbed into the bloodstream by the kidney, so that blood volume decreases and urine volume increases. This lowers blood pressure and prevents excess fluid accumulation in heart failure. Metolazone is sometimes used together with loop diuretics such as furosemide or bumetanide,
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