Zosuquidar trihydrochloride - CAS# 167465-36-3 Size:Solid 10 mg 7 nM for CK1ε

7 nM for CK1ε

1618672-71-1

inhibits the increase in hind paw volumes during the 2 wk of treatment by 50% at a dose of 1 mg/kg and >95% at doses of 3 or 10 mg/kg

5-bis(2-hydroxyphenyl)-1

InChiKey: AHYMHWXQRWRBKT-UHFFFAOYSA-N

Zosuquidar trihydrochloride - CAS# 167465-36-3 Size:Solid 10 mg 7 nM for CK1εZosuquidar, also known as LY 335979, is a potent P glycoprotein (P gp) inhibitor, which binds with high affinity to P glycoprotein and inhibits P glycoprotein mediated multidrug resistance (MDR). P glycoprotein, encoded by the MDR 1 gene, is a member of the ATP binding cassette superfamily of transmembrane transporters and prevents the intracellular accumulation of many natural product derived cytotoxic agents. Product information CAS Number: 167465