Consider cards that provide broad answers to common permanent types
Yes, believe it or not, we have a policy that Magic cards have to do what they say
Plus, they often get exclusive bundles or older sets that are harder to find elsewhere

Abigale, Eloquent First-Year Abigale, Poet Laureate Aegis Sculptor Ambrosia Whiteheart Aven Interrupter Balmor, Battlemage Captain Bartz and Boko Black Chocobo Blacksnag Buzzard Buzzard-Wasp Colony Cat-Owl Choco, Seeker of Paradise City Pigeon Clinquant Skymage Coveted Falcon Crow of Dark Tidings Curious Farm Animals Dragonhawk, Fate's Tempest Dreadwing Scavenger East Wind Avatar Elemental Mascot Empyrean Eagle Encouraging Aviator Featherbrained Filcher Finch Formation Hardened Academic Harrier Strix Healer's Hawk High-Flying Ace Iguana Parrot Jackdaw Savior Kastral, the Windcrested Kishla Skimmer Knightfisher Koya, Death from Above Kykar, Zephyr Awakener Lifecreed Duo Lotusguard Disciple Maha, Its Feathers Night Messenger Hawk Miner's Guidewing Mockingbird Monastery Messenger Moseo, Vein's New Dean Ostrich-Horse Otter-Penguin Owlin Historian Pet Avengers Pileated Provisioner Plumecreed Escort Plumecreed Mentor Raven Eagle Raven of Fell Omens Resilient Roadrunner Salvation Swan Sazh's Chocobo Seedpod Squire Shrike Force Sinkhole Surveyor Skycoach Conductor Skyskipper Duo Slickshot Show-Off Spellbook Seeker Sterling Supplier Stirring Hopesinger Strix Lookout Summon: Choco/Mog Summon: Fat Chocobo Sunbird Effigy Swiftwing Assailant Tempest Hawk The Goose Mother
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If you are just playing the card straight up, its kind of a build your own Thoughtseize. That said, it was always particularly powerful that you could ensure your opponent doesnt have the card that can stop you, since even if you missed, it meant they didnt have that card
That cultural gravity translates directly and powerfully into the trading card market, where Mewtwo cards consistently rank among the most valuable and sought-after in the hobby